The Synthesis of Atomoxetine-containing Carboxamides - Potential Human Carbonic Anhydrase Inhibitors

Shetnev, Anton A. and Osipyan, Angelina T. and Sapegin, Alexander V. and Dorogov, Mikhail V. (2016) The Synthesis of Atomoxetine-containing Carboxamides - Potential Human Carbonic Anhydrase Inhibitors. American Chemical Science Journal, 10 (3). pp. 1-5. ISSN 22490205

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Abstract

The method of synthesis of Atomoxetine is developed, including enzyme-catalyzed stereospecific reduction 3-chloro-1-phenyl-propan-1-one and Mitsunobu condensation with a chiral alcohol, and o-cresol. New potential human carbonic anhydrase inhibitors were obtained via reaction Atomoxetine with carboxylic derivatives of benzene and thiophene containing primary sulfonamide moiety.

Item Type: Article
Subjects: Article Archives > Chemical Science
Depositing User: Unnamed user with email support@articlearchives.org
Date Deposited: 16 Jun 2023 05:48
Last Modified: 20 Sep 2025 03:52
URI: http://community.sent2promo.com/id/eprint/1422

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